Allergic vasculitis

Hypersensitivity to a drug or foreign agent leads to a skin disorder with inflammation and damage to blood vessels of the skin.

Alternative Names

Vasculitis; Vasculitis - allergic; Vasculitis - hypersensitivity

Causes, incidence, and risk factors

Vasculitis occurs because of inflammation and damage to blood vessels. The inflammation of allergic vasculitis is the result of an allergic reaction to a drug or other foreign agent.

Signs and tests

The diagnosis is primarily based on a history of skin lesions that develop after exposure to medications or a foreign substance ( antigen ) and the clinical presentation (pattern of symptoms).

  • The
  • ESR ( sed rate ) may be elevated.
  • Skin biopsy
  • shows vasculitis (inflammation of the blood vessels).
  • This disease may also alter the results of a platelet aggregation test .


    Treatment is aimed at reducing the inflammation, allowing the natural healing process to occur. If possible, stop exposure to the causative medication (or other antigen ). Aspirin or corticosteroids may be prescribed to reduce inflammation of the blood vessels. (DO NOT give aspirin to children except as advised by the health care provider.) In severe cases, treatment with corticosteroids may be necessary.

    Expectations (prognosis)

    Allergic vasculitis usually resolves in time.


  • permanent damage to the blood vessels or skin with scarring
  • vasculitis affecting the internal organs (kidney, bone, and so on)
  • Calling your health care provider

    Call for an appointment with your health care provider if symptoms indicate allergic vasculitis may be present.


    Avoid exposure to medications to which there are known allergies .

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