A craniopharyngioma is a benign tumor that develops near the pituitary gland (a small endocrine gland at the base of the brain).
Causes, incidence, and risk factors
This tumor most commonly affects children between 5 and 10 years of age; however, adults can sometimes be affected. Boys and girls are equally likely to develop this condition.
Treatment
Traditionally, surgery has been the main treatment for craniopharyngioma. However, radiation treatment instead of surgery may be the best choice for some patients. In tumors that cannot be removed completely with surgery alone, radiation therapy is usually necessary. If the tumor has a classic appearance on CT scan, then even a biopsy may not be necessary, if treatment with radiation alone is planned. This tumor is best treated at a center with experience managing craniopharyngiomas.
Expectations (prognosis)
In general, the prognosis for patients with craniopharyngioma is good, with an 80-90% chance of permanent cure if the tumor can be completely removed with surgery or treated with high doses of radiation. However, the prognosis for an individual patient depends on several factors, including the ability of the tumor to be completely removed, and the neurological deficits and hormonal imbalances caused by the tumor and the treatment. Most of the problems with hormones and vision do not improve with treatment, and sometimes the treatment may even make them worse.
Complications
A significant percentage of patients have long-term hormonal, visual, and neurological problems following the treatment of craniopharyngioma. In patients where the tumor is not completely removed, the condition may recur.
Calling your health care provider
Call your health care provider if there are any signs of increased intracranial pressure (headache, nausea, vomiting, imbalance), any visual changes, increased thirst and urination, or poor growth in a child.