Ganglioneuroblastoma is a tumor arising from nerve tissue which is intermediate between benign (slow-growing and unlikely to spread) and malignant (fast-growing, aggressive, and likely to spread).
Causes, incidence, and risk factors
This rare tumor has a yearly occurrence of less than 5 per million children. Tumors of the nervous system vary in the degree of differentiation, which determines how they appear under the microscope and whether or not they are likely to spread. Benign tumors are less likely to spread. Malignant tumors are aggressive, grow quickly, and often spread. A ganglioneuroma is a benign tumor, while a neuroblastoma (occurring in children more than a year old) is generally malignant. A ganglioneuroblastoma may be localized to one area or widespread, but is usually less aggressive than a neuroblastoma. The cause is unknown.
Treatment
Because these tumors are rare, they should be treated at a specialist center by experts who have previous experience with them. Depending on the specific nature of the tumor, treatment may consist of surgery and possibly chemotherapy and radiation therapy.
Support groups
The stress of illness can often be helped by joining a support group where members share common experiences and problems. See cancer - support group .
Expectations (prognosis)
The prognosis depends on the extent of the tumor and whether or not some areas of the tumor contain the more aggressive cells of a neuroblastoma.
Calling your health care provider
Call your health care provider if you feel a mass or growth on your child's body. Make sure children receive routine examinations as part of their well child care.